BDBM50118220 (ppA)2::A(5')p4(5')A::CHEMBL339385::P(1),P(4)-bis(5'-adenosyl) tetraphosphate::adenosine(5')tetraphospho(5')adenosine::bis(5'-adenylyl) diphosphate

SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O

InChI Key InChIKey=YOAHKNVSNCMZGQ-XPWFQUROSA-N

Data  2 IC50  8 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50118220   

TargetP2Y purinoceptor 2(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118220((ppA)2 | A(5')p4(5')A | CHEMBL339385 | P(1),P(4)-b...)
Affinity DataEC50:  720nMAssay Description:Evaluated for agonist activity against phospholipase C coupled recombinant human P2Y purinoceptor 2 (P2Y2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118220((ppA)2 | A(5')p4(5')A | CHEMBL339385 | P(1),P(4)-b...)
Affinity DataEC50:  167nMAssay Description:Agonist activity at N-terminal HA epitope-tagged wild type 4 human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellula...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2Y purinoceptor 2(Homo sapiens (Human))
National Institute Of Diabetes

Curated by ChEMBL
LigandPNGBDBM50118220((ppA)2 | A(5')p4(5')A | CHEMBL339385 | P(1),P(4)-b...)
Affinity DataEC50:  145nMAssay Description:Agonist activity at N-terminal HA epitope-tagged wild type 3 human P2Y2 receptor expressed in human 1321N1 cells assessed as increase in intracellula...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed